Adaptive resistance to aminoglycoside antibiotics in Pseudomonas aeruginosa

Lability of Resistance to Aminoglycoside Antibiotics in Pseudomonas Aeruginosa

The determinants for resistance to aminoglycoside antibiotics in some strains of Pseudomonas aeruginosa were irreversively lost during storage or by treatment with ethidium bromide. This fact has indicated the presence of plasmids governing resistance to aminoglycosides in the pseudomonads as well as R factor in gram-negative enteric bacteria and plasmid in staphylococci. Many papers have descr...

Aminoglycoside resistance in Pseudomonas aeruginosa.

In vitro characterization of aminoglycoside adaptive resistance in Pseudomonas aeruginosa.

Aminoglycoside adaptive resistance was characterized in one reference strain and four clinical isolates of Pseudomonas aeruginosa. Adaptive resistance was initiated with a 2-h gentamicin or tobramycin exposure at the MIC. Each P. aeruginosa strain demonstrated an adaptive-resistance period of between 8 and 12 h when tested with both aminoglycosides. Aminoglycoside adaptive resistance was shown ...

Polyamines induce resistance to cationic peptide, aminoglycoside, and quinolone antibiotics in Pseudomonas aeruginosa PAO1.

Pseudomonas aeruginosa, a gram-negative bacterium of human pathogens, is noted for its environmental versatility, enormous metabolic capacity, and resistance to antibiotics. Overexpression of the outer membrane protein OprH and increased resistance to polycationic peptide antibiotics (e.g., polymyxin B) mediated by the PhoPQ two-component system on induction of a putative lipopolysaccharide (LP...

Pseudomonas aeruginosa serotypes and resistance to antibiotics from wound swabs.

INTRODUCTION/AIM Pseudomonas aeruginosa (P. aeruginosa) is the most common cause of wound infections, following the disruption of the skin or mucous membranes integrity. The aim of this study was to analyze of the presence P. aeruginosa in wound swabs, antibiotics susceptibility testing, determination of the minimum inhibitory concentrations (MICs) of antibiotics, testing of the metallo-β-lacta...